ZYE ALX® · 755 nm Alexandrite · SmartLASER Technology
Advanced alexandrite.
Intelligent by design.
The ZYE ALX® features VYDENCE's innovative SmartLASER technology — enabling quick, safe, and effective treatments while capturing real-time IoT analytics. Its 755 nm alexandrite delivers fast, comfortable hair removal for Skin Types I–IV, with versatile pigmentation and vascular capabilities — and no consumables, ever.
ZYE ALX® · 755 nm
The ZYE ALX® Platform by VYDENCE
SUPER POWERFUL.
SUPER INTELLIGENT.
The ZYE ALX® brings next-generation intelligence to alexandrite laser treatments — combining near-100 treatment indications with proprietary SmartLASER technology, the most complete handpiece ecosystem in the industry, and the only 2-year comprehensive warranty in the category.
Advanced 755 nm alexandrite laser platform engineered for fast, comfortable hair removal on Skin Types I–IV — with versatile pigmentation and vascular capabilities. Compatible with the shared VYDENCE handpiece ecosystem plus 4 next-generation fiber optic handpieces.
Higher energy even on larger spot sizes — enhancing treatment efficacy regardless of the treatment area.
SmartLASER technology enables remote technical monitoring and real-time IoT analytics for platform usage management.
Nearly 100 indications per platform, with handpieces you can add as your practice grows — maximizing ROI.
Optimize practice revenue and focus on delivering patient results — zero per-shot or consumable costs.
755 nm alexandrite — ideal for Skin Types I–IV
Fast, comfortable hair removal across large areas
Effective on brown spots and pigmented lesions
3 fiber delivery choices for long- and short-pulse
Contact cooling + color air chiller options
Compatible with the shared VYDENCE handpiece ecosystem
Proprietary Intelligence
SmartLASER™
Technology
Every ZYE ALX® is equipped with VYDENCE's proprietary SmartLASER technology — a connected intelligence layer that goes beyond the treatment room to help you monitor, manage, and grow your laser practice with data-driven confidence.
- Remote technical monitoring — reduce downtime, accelerate support
- Real-time IoT analytics for platform usage and treatment data
- Online platform management from anywhere
- Quick, safe, and effective treatment protocols built in
- Engineered by Brazil's premier laser company — trusted globally
- 2-year comprehensive warranty — the only platform offering full coverage
Next-Generation Fiber Optic Handpieces
EXCLUSIVE ZYE®
HANDPIECE INNOVATIONS.
In addition to the shared VYDENCE handpiece ecosystem, the ZYE ALX® supports proprietary next-generation fiber optic handpieces with exclusive technologies unavailable on any other platform.
Exclusive Technologies
3-10/VL® · 8-18/HR®
ZYE Telescope® System
The ZYE Telescope® integrates digital optical zoom directly into the handpiece, enabling fast, tool-free spot size adjustment across different treatment areas without interrupting the session. Larger spot sizes maintain full energy delivery — no trade-off between coverage area and fluence. Ideal for providers who need to move efficiently between facial and body zones within a single appointment.
8-18/HR®
FLAT-FRAME® Technology
Traditional round laser spots leave gaps between pulses, requiring overlapping passes that slow treatment and risk uneven coverage. FLAT-FRAME® uses a square spot geometry to eliminate those gaps entirely — delivering a 25% larger effective treatment area per pulse with seamless, uniform coverage. The result is faster sessions, fewer passes, and more consistent outcomes across large body areas like the back, legs, and chest.
3-10/VL® · 8-18/HR®
COOL-&-CLEAR® Sapphire
COOL-&-CLEAR® uses an integrated sapphire contact cooling window that chills the skin surface immediately before, during, and after each pulse — protecting the epidermis while allowing higher fluences to be delivered safely at depth. Unlike gel-based cooling or external cryo devices, the sapphire tip maintains direct skin contact throughout treatment, ensuring consistent thermal protection and enhanced procedural safety without interrupting the workflow.
3-24/HR®
3-24/HR® Large-Area Handpiece
The 3-24/HR® delivers plug-and-play spot sizes up to 24 mm in diameter — one of the largest available in the category — with integrated air cooling for continuous comfortable delivery. Its large spot footprint dramatically reduces the number of pulses needed to cover the back, thighs, or chest, cutting treatment time significantly. With 11 available spot size configurations and an epidermal cooling adapter that requires no consumables, it's optimized for high-volume hair removal practices.
3-24/HR®
AccuSense® Sensor
AccuSense® provides real-time, continuous skin temperature monitoring throughout treatment — not just a single pre-treatment reading. The sensor dynamically reads surface temperature pulse-by-pulse and allows the provider to set customizable safety thresholds, automatically flagging deviations before they become a safety concern. This level of real-time feedback is particularly valuable when treating variable tissue types, darker skin tones, or large body areas where skin response can shift across the session.
Full Shared Ecosystem
Also Compatible With
VYDENCE Handpieces
ZYE platforms share the same plug-and-play handpiece ecosystem as the Etherea MX® — meaning any handpiece you add works across your entire VYDENCE investment.
~100 Indications Per Platform
TREAT MORE.
GROW MORE.
The ZYE ALX® addresses a comprehensive range of aesthetic indications — across hair, pigmentation, and vascular — with more added through the VYDENCE handpiece ecosystem.
Hair Removal
Fast, comfortable permanent hair reduction — the 755 nm alexandrite is ideal for Skin Types I–IV.
Pigmented Lesions
The 755 nm alexandrite wavelength addresses sunspots, lentigines, and unwanted brown spots precisely.
Large Body Areas
FLAT-FRAME® and the 3-24/HR® cut pulses and passes across the back, legs, and chest.
Vascular Lesions
LongPulse® and IPL-Sq® handpieces target spider veins, rosacea, and diffuse redness.
Rosacea
3-24/HR® handles vascular lesion treatments and rosacea with plug-and-play ease across large areas.
Acne Scars
The ProDeep® handpiece treats acne scars with non-ablative fractional resurfacing and no downtime.
Tattoo & Pigment
The ACROMA-QS® handpiece adds nanosecond Q-switched tattoo removal and benign pigment treatment.
Skin Types I–IV
ZYE ALX is ideal for Fitzpatrick Types I–IV. Pair with ZYE YAG for coverage across all skin types.
Clinically Proven Results
REAL RESULTS.
REAL PATIENTS.
Individual results may vary. Each treatment is tailored to the patient's specific concerns, skin type, and protocol.
* Results may vary. Individual outcomes depend on treatment protocol, skin type, and patient compliance. Images courtesy of VYDENCE® Medical and contributing physicians.
Trusted by Laser Experts
TRUSTED BY CLINICIANS
ACROSS THE COUNTRY
Real feedback from physicians and providers who've incorporated VYDENCE ZYE platforms into their practices.
We have incorporated the VYDENCE ZYE platform in our office and it has been super successful. One of the standouts has been the handPICO, which has quickly become an office favorite for low-density lentigines and melasma, plus the versatility for tattoo removal. The ProDeep handpiece has been huge for non-ablative fractional help with acne scars when patients don't want any downtime.
I'm finding it remarkable in that it's very flexible, has minimum downtime and provides a high level of patient comfort. The ProDeep® 1340-nm handpiece gives us a wavelength that is unique to the US market — we're now able to effectively treat conditions we weren't able to in the past, like acne and hidradenitis suppurativa. It should be the core piece of any practice.
The versatility and performance of this platform have exceeded my expectations. I'm excited to continue exploring all that these powerful technologies have to offer and to see the growing impact on my patients' skin health and confidence.
By the Numbers
ZYE ALX®
AT A GLANCE
Manufacturer: VYDENCE Medical · Distributed by MRP
Available Through MRP
GET IN TOUCH
Fill out the form below to connect with MRP about the ZYE ALX®. We'll be in touch shortly.